Association between insulin resistance and vascular damage in an adult population in China: a cross-sectional study

Bibliographic Details
Title:	Association between insulin resistance and vascular damage in an adult population in China: a cross-sectional study
Authors:	Cong Ma, Bokai Cheng, Lin Zhou, Shuang Cai, Bangguo Qin, Jin Sun, Man Li, Shuaishuai Zhang, Yue Chen, Qiligeer Bao, Ping Zhu, Guogang Xu, Shuxia Wang
Source:	Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Publisher Information:	Nature Portfolio, 2024.
Publication Year:	2024
Collection:	LCC:Medicine LCC:Science
Subject Terms:	Insulin resistance, Vascular damage, HOMA-IR, Medicine, Science
More Details:	Abstract There is a relative scarcity of large-scale population studies investigating the relationship between the insulin resistance index of homeostasis model assessment (HOMA-IR) and vascular damage. Therefore, we assessed the association between HOMA-IR and vascular damage in adults aged 18 years and older in China. A total of 17,985 research subjects were included. Vascular damage markers and relevant laboratory tests were measured. HOMA-IR was calculated as (fasting insulin * fasting blood glucose)/22.5. Vascular damage included arteriosclerosis (ba-PWV > 1800 cm/s), peripheral artery disease (ABI 30 mg/g). The relationship between HOMA-IR and vascular damage was analyzed using the RCS. The restricted cubic spline (RCS) analysis suggested that HOMA-IR was nonlinearly associated with arteriosclerosis (P for no-liner
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	2045-2322
Relation:	https://doaj.org/toc/2045-2322
DOI:	10.1038/s41598-024-69338-y
Access URL:	https://doaj.org/article/f1d8fc7113224e7e85f398f9688ac7c3
Accession Number:	edsdoj.f1d8fc7113224e7e85f398f9688ac7c3
Database:	Directory of Open Access Journals
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More Details
ISSN:	20452322
DOI:	10.1038/s41598-024-69338-y
Published in:	Scientific Reports
Language:	English