Clinical application of Magnetic resonance elastography in hepatocellular carcinoma: from diagnosis to prognosis

Bibliographic Details
Title: Clinical application of Magnetic resonance elastography in hepatocellular carcinoma: from diagnosis to prognosis
Authors: Jiaxu Liang, Javier Ampuero, Javier Castell, Qiong Zhang, Sijia Zhang, Yong Chen, Manuel Romero-Gómez
Source: Annals of Hepatology, Vol 28, Iss 2, Pp 100889- (2023)
Publisher Information: Elsevier, 2023.
Publication Year: 2023
Collection: LCC:Specialties of internal medicine
Subject Terms: Magnetic resonance elastography, MRE, Hepatocellular carcinoma, HCC, Clinical application, Specialties of internal medicine, RC581-951
More Details: Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a major public health problem worldwide. Liver fibrosis is closely correlated with liver functional reserve and the risk of HCC development. Meanwhile, malignant tumors generally have high cellularity compared to benign tumors, which results in increased stiffness. Magnetic resonance elastography (MRE) has emerged as a new non-invasive technique for assessing tissue stiffness with excellent diagnostic accuracy, not only for assessing liver fibrosis but also for measuring tumor stiffness. Recent studies provide new evidence that MRE may play an important role in the management of patients with HCC and show several novel clinical applications, such as predicting the development of HCC, differentiating between benign/malignant liver lesions (FLL) and HCC pathological grades, assessing treatment response, and predicting recurrence after treatment, although some findings are controversial. Therefore, we conducted this review to summarize these novel applications of MRE in HCC patients and also discuss their limitations and future advancement.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1665-2681
Relation: http://www.sciencedirect.com/science/article/pii/S1665268122002319; https://doaj.org/toc/1665-2681
DOI: 10.1016/j.aohep.2022.100889
Access URL: https://doaj.org/article/f1c957c2f06f49abafc4b26252ac7fa5
Accession Number: edsdoj.f1c957c2f06f49abafc4b26252ac7fa5
Database: Directory of Open Access Journals
More Details
ISSN:16652681
DOI:10.1016/j.aohep.2022.100889
Published in:Annals of Hepatology
Language:English