The Relation between Volume and Outcome of Transcatheter and Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis

Bibliographic Details
Title: The Relation between Volume and Outcome of Transcatheter and Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis
Authors: Jialing He, Zhen Zhang, Han Wang, Lin Cai
Source: Cardiovascular Therapeutics, Vol 2020 (2020)
Publisher Information: Hindawi-Wiley, 2020.
Publication Year: 2020
Collection: LCC:Therapeutics. Pharmacology
LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) are standard procedures for dealing with severe aortic stenosis patients. Researchers have not carried out a systematic review of the volume-outcome relationship in TAVR and SAVR. Our study is intended to address this problem. We systemically searched databases through MEDLINE, EMBASE, PUBMED, and the Cochrane Library up to September 2019. Two reviewers independently screened for the studies and evaluated bias. We used short-term mortality (in-hospital or 30-day mortality) as an outcome. A meta-analysis of TAVR with 115,596 patients ranging from 2005 to 2016 showed a result significantly in favor of high-volume hospitals (OR 0.43 (CI 0.36-0.51)). The subgroup of population period, region, data type, and cut-off value did not show any difference. A meta-analysis of SAVR comprising 418,384 patients ranging from 1994 to 2011 revealed that the OR of short-term mortality for a high-volume hospital compared with that of a low-volume hospital was 0.73 (CI 0.71, 0.74). No difference was observed in subgroups based on population period and cut-off. In conclusion, we found that short-term mortality was lower in high-volume hospitals for both TAVR and SAVR.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1755-5914
1755-5922
Relation: https://doaj.org/toc/1755-5914; https://doaj.org/toc/1755-5922
DOI: 10.1155/2020/2601340
Access URL: https://doaj.org/article/f1ad42402993479380d268c90c083d28
Accession Number: edsdoj.f1ad42402993479380d268c90c083d28
Database: Directory of Open Access Journals
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More Details
ISSN:17555914
17555922
DOI:10.1155/2020/2601340
Published in:Cardiovascular Therapeutics
Language:English