Bibliographic Details
| Title: |
Clinical Features and Treatment Outcomes of Influenza-Associated Encephalitis and Encephalopathy: A Study on 16 Children in Vietnam |
| Authors: |
Lam Van Nguyen, Duc Sy Nguyen, Que Thi Pham, Hai Thien Do, Dien Minh Tran, Tung Viet Cao, Hai Thanh Phan, Thai Quang Pham |
| Source: |
Global Pediatric Health, Vol 11 (2024) |
| Publisher Information: |
SAGE Publishing, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Pediatrics |
| Subject Terms: |
Pediatrics, RJ1-570 |
| More Details: |
Objectives . This study aims to report clinical features and treatment outcomes of 16 cases diagnosed with post-influenza encephalopathy/encephalitis. Methods . We recorded clinical characteristics of 16 pediatric patients diagnosed with post-influenza encephalopathy/encephalitis at the Vietnam National Children’s Hospital from January 2019 to January 2021. Results . There were 87.5% infected with influenza A, with influenza A/H1pdm09 and influenza A/H3 accounting for 88.9% and 11.1% respectively, and 12.5% of participants infected with influenza B. The time from onset to the appearance of neurological symptoms was 3 days, of which perceptual changes (93.8%), hypertonia (75%), and seizures (43.8%) were prevalent neurological symptoms. The majority of cases had normal cerebrospinal fluid. Cranial CT/MRI imaging revealed abnormalities in 87.5% of patients. 56.3% of patients had sequelae, including epilepsy and cerebral palsy; 25% recovered, and 18.8% died after treatment. Conclusions . Influenza-associated encephalitis/encephalopathy is a complication occurring early in children, with high mortality and sequelae rates. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2333-794X
2333794X |
| Relation: |
https://doaj.org/toc/2333-794X |
| DOI: |
10.1177/2333794X241286549 |
| Access URL: |
https://doaj.org/article/f153de9d659646ee8c3810713589746f |
| Accession Number: |
edsdoj.f153de9d659646ee8c3810713589746f |
| Database: |
Directory of Open Access Journals |
