Bibliographic Details
| Title: |
Applications of a Rapid and Sensitive Dengue DUO Rapid Immunochromatographic Test Kit as a Diagnostic Strategy during a Dengue Type 2 Epidemic in an Urban City. |
| Authors: |
Hsin-I Shih, Hsiang-Chin Hsu, Chi-Jung Wu, Chih-Hao Lin, Chia-Ming Chang, Yi-Fang Tu, Chih-Chia Hsieh, Chih-Hsien Chi, Tzu-Ching Sung |
| Source: |
PLoS ONE, Vol 11, Iss 7, p e0158437 (2016) |
| Publisher Information: |
Public Library of Science (PLoS), 2016. |
| Publication Year: |
2016 |
| Collection: |
LCC:Medicine
LCC:Science |
| Subject Terms: |
Medicine, Science |
| More Details: |
Dengue infection is a major health problem in tropical and subtropical countries. A prospective observational study in a university-affiliated hospital was conducted between August 2015 and September 2015. Patients who visited the emergency department (ED) with a presentation of any symptoms of dengue were eligible for the dengue non-structural protein 1 (NS1), IgM/IgG rapid immunochromatographic tests and real-time polymerase chain reaction (RT-PCR) to evaluate the performance of the rapid tests. Considering the RT-PCR as the gold standard for the dengue diagnosis, the ideal primary results of sensitivity (80-100%), specificity (60-84%), positive predicted value(75%-95%), and negative predicted value (70-100%) suggested that the NS1-based test with or without a combination of IgM and IgG tests have good diagnostic performances in detecting dengue infections, even in the afebrile or elderly populations. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1932-6203 |
| Relation: |
http://europepmc.org/articles/PMC4945082?pdf=render; https://doaj.org/toc/1932-6203 |
| DOI: |
10.1371/journal.pone.0158437 |
| Access URL: |
https://doaj.org/article/f0d8b6004f604525bfc676908a53d243 |
| Accession Number: |
edsdoj.f0d8b6004f604525bfc676908a53d243 |
| Database: |
Directory of Open Access Journals |
