The individual blood cell telomere attrition rate is telomere length dependent.

Bibliographic Details
Title:	The individual blood cell telomere attrition rate is telomere length dependent.
Authors:	Katarina Nordfjäll, Ulrika Svenson, Karl-Fredrik Norrback, Rolf Adolfsson, Per Lenner, Göran Roos
Source:	PLoS Genetics, Vol 5, Iss 2, p e1000375 (2009)
Publisher Information:	Public Library of Science (PLoS), 2009.
Publication Year:	2009
Collection:	LCC:Genetics
Subject Terms:	Genetics, QH426-470
More Details:	Age-associated telomere shortening is a well documented feature of peripheral blood cells in human population studies, but it is not known to what extent these data can be transferred to the individual level. Telomere length (TL) in two blood samples taken at approximately 10 years interval from 959 individuals was investigated using real-time PCR. TL was also measured in 13 families from a multigenerational cohort. As expected, we found an age-related decline in TL over time (r = -0.164, P
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	1553-7390 1553-7404
Relation:	http://europepmc.org/articles/PMC2633043?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404
DOI:	10.1371/journal.pgen.1000375
Access URL:	https://doaj.org/article/f016543d74054b989cc75fa1e3281cbf
Accession Number:	edsdoj.f016543d74054b989cc75fa1e3281cbf
Database:	Directory of Open Access Journals