Risk factors and prognoses of invasive Candida infection in surgical critical ill patients with perforated peptic ulcer

Bibliographic Details
Title: Risk factors and prognoses of invasive Candida infection in surgical critical ill patients with perforated peptic ulcer
Authors: Yia-Ting Li, Yao-Chen Wang, Shun-Fa Yang, Yat-Yin Law, Bei-Hao Shiu, Te-An Chen, Shih-Chi Wu, Min-Chi Lu
Source: Journal of Microbiology, Immunology and Infection, Vol 55, Iss 4, Pp 740-748 (2022)
Publisher Information: Elsevier, 2022.
Publication Year: 2022
Collection: LCC:Microbiology
Subject Terms: Perforated peptic ulcer, Invasive Candida infection, Risk factors, Prognoses, Microbiology, QR1-502
More Details: Background: The risk of invasive Candida infection (ICI) is high in patients with perforated peptic ulcer (PPU) who received laparotomy or laparoscopic surgery, but the risk factors and predictors of morbidity outcomes remain uncertain. This study aims to identify the risk factors of ICI in surgical critically ill PPU patients and to evaluate the impact on patient's outcomes. Methods: This is a single-center, retrospective study, with a total of 170 surgical critically ill PPU patients. Thirty-seven patients were ICI present and 133 were ICI absent subjects. The differences in pulmonary complications according to invasive candidiasis were determined by the Mann–Whitney U test. Evaluation of predictors contributing to ICI and 90-day mortality was conducted by using multivariate logistic regression analysis. Results: Candida albicans was the primary pathogen of ICI (74.29%). The infected patients had higher incidence of bacteremia (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1684-1182
Relation: http://www.sciencedirect.com/science/article/pii/S1684118222000275; https://doaj.org/toc/1684-1182
DOI: 10.1016/j.jmii.2022.03.001
Access URL: https://doaj.org/article/bfbbfa627fda428aa536fda1210424a8
Accession Number: edsdoj.bfbbfa627fda428aa536fda1210424a8
Database: Directory of Open Access Journals
More Details
ISSN:16841182
DOI:10.1016/j.jmii.2022.03.001
Published in:Journal of Microbiology, Immunology and Infection
Language:English