Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping

Bibliographic Details
Title: Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping
Authors: Laura Sachs, Jan Wesche, Lea Lenkeit, Andreas Greinacher, Markus Bender, Oliver Otto, Raghavendra Palankar
Source: Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Publisher Information: Nature Portfolio, 2022.
Publication Year: 2022
Collection: LCC:Biology (General)
Subject Terms: Biology (General), QH301-705.5
More Details: Sachs et al. examine the effects of different ex vivo anticoagulants on the biomechanical and functional properties of single platelets using high-throughput real-time fluorescence and deformability cytometry (RT-FDC). Their results demonstrate that the choice of ex vivo anticoagulant may strongly impact the outcomes of mechanophenotyping.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2399-3642
Relation: https://doaj.org/toc/2399-3642
DOI: 10.1038/s42003-021-02982-6
Access URL: https://doaj.org/article/ebf798288a724bac870b04d7f236b094
Accession Number: edsdoj.bf798288a724bac870b04d7f236b094
Database: Directory of Open Access Journals
More Details
ISSN:23993642
DOI:10.1038/s42003-021-02982-6
Published in:Communications Biology
Language:English