Bibliographic Details
| Title: |
Association of visceral adiposity and clinical outcome among patients with aldosterone producing adenoma |
| Authors: |
Leay Kiaw Er, Meng-Chun Lin, Yao-Chou Tsai, Jong-Kai Hsiao, Chung-Yi Yang, Chin-Chen Chang, Kang-Yung Peng, Jeff S Chueh, Tai-Shuan Lai, Shao-Yu Yang, Kao-Lang Liu, Bo-Chiag Lee, Shuo-Meng Wang, Kuo-How Huang, Po-Chih Lin, Lian-Yu Lin, Shih-Cheng Liao, Ruoh-Fang Yen, Ching-Chu Lu, Chieh-Kai Chan, Leay-Kiaw Er, Ya-Hui Hu, Chia-Hui Chang, Che-Hsiung Wu, Shih-Chieh Jeff Chueh, Chen-Hsun Ho, Wei-Chieh Huang, Ying-Ying Chen |
| Source: |
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020) |
| Publisher Information: |
BMJ Publishing Group, 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| Subject Terms: |
Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| More Details: |
Introduction Primary aldosteronism (PA) is a common form of secondary hypertension that has significant cardiovascular events and increased prevalence of metabolic syndrome and diabetics. Although plasma aldosterone concentration is positively correlated with visceral fat area (VFA) in non-PA individuals, the role of visceral adiposity associated with clinical success after surgery is not known.Research design and methods We analyzed patients who underwent adrenalectomy for aldosterone-producing adenoma (APA) at the Taiwan PA Investigator group. VFA was calculated from the abdominal CT scan at APA diagnosis, and all patients received adrenalectomy.Results The study involved 100 consecutive patients with APA (42 males; mean age 49.3 years) matched with 41 essential hypertension (EH) patients. Patients with APA had smaller VFA (p=0.010) than their EH counterparts. Multiple linear regression analysis revealed that the duration of hypertension (p=0.007), but not plasma aldosterone, was negatively correlated with VFA in patients with APA. Logistic regression analysis showed that log VFA (OR=0.065, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2052-4897 |
| Relation: |
https://drc.bmj.com/content/8/1/e001153.full; https://doaj.org/toc/2052-4897 |
| DOI: |
10.1136/bmjdrc-2019-001153 |
| Access URL: |
https://doaj.org/article/bf6151fd51d743459575b09543e35bf7 |
| Accession Number: |
edsdoj.bf6151fd51d743459575b09543e35bf7 |
| Database: |
Directory of Open Access Journals |
