| Title: |
Case Report: The Use of Intravenous SMOFlipid Infusion to Treat Severe Asparaginase-Induced Hypertriglyceridemia in Two Pediatric Acute Lymphoblastic Leukemia Patients |
| Authors: |
Sie Chong Doris Lau, C-Khai Loh, Hamidah Alias |
| Source: |
Frontiers in Pediatrics, Vol 9 (2021) |
| Publisher Information: |
Frontiers Media S.A., 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Pediatrics |
| Subject Terms: |
acute lymphoblastic leukemia, asparaginase, hypertriglyceridemia, omega-3, SMOFlipid, pediatric, Pediatrics, RJ1-570 |
| More Details: |
Asparaginase-induced hypertriglyceridemia can have a spectrum of clinical presentations, from being asymptomatic to having life-threatening thrombosis or hyperviscosity syndrome. At present, there is no recommendation on routine lipid monitoring during asparaginase-containing treatment phase, nor a standardized guideline on its management. Two cases are presented here to illustrate the effects of concurrent infection on asparaginase-induced hypertriglyceridemia in patients with high-risk ALL and the use of SMOFlipid infusion as a treatment option in an acute situation. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-2360 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fped.2021.660627/full; https://doaj.org/toc/2296-2360 |
| DOI: |
10.3389/fped.2021.660627 |
| Access URL: |
https://doaj.org/article/beaddf7ababb4a04b7a7eab63c8c75fa |
| Accession Number: |
edsdoj.beaddf7ababb4a04b7a7eab63c8c75fa |
| Database: |
Directory of Open Access Journals |
