Bibliographic Details
| Title: |
Red blood cell triglycerides—a unique pool that incorporates plasma-free fatty acids and relates to metabolic health |
| Authors: |
Yilin Song, Michael D. Jensen |
| Source: |
Journal of Lipid Research, Vol 62, Iss , Pp 100131- (2021) |
| Publisher Information: |
Elsevier, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Biochemistry |
| Subject Terms: |
cholesterol, obesity, hyperlipidemia, fatty acid, triglyceride, weight loss, Biochemistry, QD415-436 |
| More Details: |
Most research into red blood cell (RBC) lipids focuses on membrane phospholipids and their relationships to metabolic conditions and diet. Triglycerides (TGs) exist in most cells; the TG-fatty acids serve as readily available fuel for oxidative phosphorylation. Because RBCs lack mitochondria, they would not be expected to store fatty acids in TG. We followed up on a previous in vitro study that found FFA can be incorporated into RBC-TG by testing whether intravenously infused [U-13C]palmitate could be detected in RBC-TG. We also quantified RBC-TG fatty acid concentrations and profiles as they relate to plasma FFA and lipid concentrations. We found that 1) RBC-TG concentrations measured by glycerol and LC/MS were correlated (r = 0.77; P < 0.001) and averaged |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
0022-2275 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S0022227521001139; https://doaj.org/toc/0022-2275 |
| DOI: |
10.1016/j.jlr.2021.100131 |
| Access URL: |
https://doaj.org/article/bd10392df0374566a1d153186eaa5d4a |
| Accession Number: |
edsdoj.bd10392df0374566a1d153186eaa5d4a |
| Database: |
Directory of Open Access Journals |
