Bibliographic Details
| Title: |
Factors correlating with serum birch pollen IgE status in pregnant women in Hokkaido, Japan: The Japan Environment and Children's Study (JECS) |
| Authors: |
Yasuaki Saijo, Eiji Yoshioka, Yukihiro Sato, Toshinobu Miyamoto, Kazuo Sengoku, Yoshiya Ito, Sachiko Itoh, Chihiro Miyashita, Atsuko Araki, Reiko Kishi, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Zentaro Yamagata, Hidekuni Inadera, Takeo Nakayama, Hiroyasu Iso, Masayuki Shima, Youichi Kurozawa, Narufumi Suganuma, Koichi Kusuhara, Takahiko Katoh |
| Source: |
World Allergy Organization Journal, Vol 13, Iss 6, Pp 100128- (2020) |
| Publisher Information: |
Elsevier, 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Immunologic diseases. Allergy |
| Subject Terms: |
Birch pollen, Sensitization, IgE, Allergic rhinitis, Pregnant women, Immunologic diseases. Allergy, RC581-607 |
| More Details: |
Background: Birch pollen allergy affects pregnant women, and such allergy may affect the development of allergic diseases in their children. Using nationwide birth cohort data, this study aimed to investigate the prevalence of birch pollen IgE positivity and to identify correlating factors in pregnant women in Hokkaido, Japan, a high-latitude island. Methods: Participants included 6856 pregnant women. Participants responded to questionnaires regarding lifestyle factors and history of allergies. Data regarding parity, height, and pre-pregnancy weight were collected from medical records. Blood samples were obtained from participants during the first trimester of pregnancy, and serum allergen-specific IgE titers were determined. Results: The serum of 30.2% participants was positive for birch pollen IgE (≥0.35 UA/mL). Such positivity significantly correlated with a history of other allergic diseases, particularly food allergy and allergic rhinitis/hay fever. In multivariate logistic regression analysis, pre-pregnancy high body mass index (BMI ≥ 25) significantly correlated with birch pollen IgE positivity [odds ratio (OR), 1.24; 95% CI, 1.05–1.47; reference BMI, 18.5–24.9] and higher income (≥10 million yen per year; OR,0.55; 95% CI, 0.37–0.81; reference, household income |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1939-4551 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1939455120300314; https://doaj.org/toc/1939-4551 |
| DOI: |
10.1016/j.waojou.2020.100128 |
| Access URL: |
https://doaj.org/article/abc48b2eb30a4e3c992e489eebde70c7 |
| Accession Number: |
edsdoj.bc48b2eb30a4e3c992e489eebde70c7 |
| Database: |
Directory of Open Access Journals |
