Bibliographic Details
| Title: |
Ultrasensitive electrochemiluminescence immunosensor with wide linear range based on a multiple amplification approach |
| Authors: |
Xiao-Lei Huo, Nan Zhang, Jing-Juan Xu, Hong-Yuan Chen |
| Source: |
Electrochemistry Communications, Vol 98, Iss , Pp 33-37 (2019) |
| Publisher Information: |
Elsevier, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Chemistry |
| Subject Terms: |
Industrial electrochemistry, TP250-261, Chemistry, QD1-999 |
| More Details: |
An ultrasensitive and highly selective electrochemiluminescence (ECL) immunosensor is proposed for the detection of prostate specific antigen (PSA) based on multiple amplification via glucose oxidase (GOx) and platinum nanoparticles (Pt NPs) conjugated with polyglutamic acid (PGA). The proposed immunosensor has a wide linear range (1.0 pg/mL–150 ng/mL) and low detection limit (0.6 pg/mL) for PSA detection, which is due in part to the excellent catalytic activity of the Ab2-GOx-PGA-Pt NPs probe toward the luminol ECL reaction. Keywords: Ultrasensitive, Electrochemiluminescence, Multiple amplification, PGA, PSA |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1388-2481 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1388248118302996; https://doaj.org/toc/1388-2481 |
| DOI: |
10.1016/j.elecom.2018.11.014 |
| Access URL: |
https://doaj.org/article/bc02341a679f415b80fc987d3d7840e2 |
| Accession Number: |
edsdoj.bc02341a679f415b80fc987d3d7840e2 |
| Database: |
Directory of Open Access Journals |
