Academic Journal
Neutrophil to lymphocyte ratio as an assessment tool to differentiate between uterine sarcoma and myoma: a systematic review and meta-analysis
| Title: | Neutrophil to lymphocyte ratio as an assessment tool to differentiate between uterine sarcoma and myoma: a systematic review and meta-analysis |
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| Authors: | Fatemeh Tabatabaei, Saghar Babadi, Shima Nourigheimasi, Arshin Ghaedi, Monireh Khanzadeh, Aida Bazrgar, Morad Kohandel Gargari, Shokoufeh Khanzadeh |
| Source: | BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024) |
| Publisher Information: | BMC, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: | Neutrophil to lymphocyte ratio, NLR, Uterine sarcoma, Uterine leiomyoma, Meta-analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: | Abstract Background This systematic review and meta-analysis aimed to determine the potential value of neutrophil to lymphocyte ratio (NLR) as an assessment tool in the clinical distinction between uterine sarcoma and uterine leiomyoma. Methods We comprehensively searched Web of Science, Scopus, and PubMed for relevant papers published before March 19, 2023. The standardized mean difference (SMD) was provided, along with a 95% confidence interval (CI). The random-effects model was employed to derive pooled effects due to the high levels of heterogeneity. The Newcastle-Ottawa scale was used for the quality assessment. Our study was registered in PROSPERO (CRD42023478331). Results Overall, seven articles were included in the analysis. A random-effect model revealed that patients with uterine sarcoma had higher NLR levels compared to those with uterine myoma (SMD = 0.60, 95% CI = 0.22–0.98; p = 0.002). In the subgroup analysis according to sample size, we found that patients with uterine sarcoma had elevated levels of NLR compared to those with uterine myoma in either large studies (SMD = 0.58, 95% CI = 0.04–1.13; P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1471-2407 68048661 |
| Relation: | https://doaj.org/toc/1471-2407 |
| DOI: | 10.1186/s12885-023-11775-5 |
| Access URL: | https://doaj.org/article/ba7c39d919c34addb6cd5f680486616d |
| Accession Number: | edsdoj.ba7c39d919c34addb6cd5f680486616d |
| Database: | Directory of Open Access Journals |
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| ISSN: | 14712407 68048661 |
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| DOI: | 10.1186/s12885-023-11775-5 |
| Published in: | BMC Cancer |
| Language: | English |