HLA types in Turkish children with celiac disease
| Title: | HLA types in Turkish children with celiac disease |
|---|---|
| Authors: | Zarife Kuloğlu, Tümay Doğanci, Aydan Kansu, Fulya Demirçeken, Murat Duman, Hüseyin Tutkak, Arzu Ensari, Nurten Girgin |
| Source: | The Turkish Journal of Pediatrics, Vol 50, Iss 6 (2008) |
| Publisher Information: | Hacettepe University Institute of Child Health, 2008. |
| Publication Year: | 2008 |
| Collection: | LCC:Pediatrics |
| Subject Terms: | Pediatrics, RJ1-570 |
| More Details: | The aim of this study was to assess the distribution of human leukocyte antigen (HLA) groups in Turkish children with celiac disease (CD) and to investigate the association of HLA types and clinical manifestations of CD. Seventy-five children with CD were evaluated in two groups: Group I consisted of 45 classical celiac patients (15 males, 6.7+/-3.8 years); Group II consisted of 30 atypical celiac patients (9 males, 9.3+/-4.3 years). The control group consisted of 100 healthy renal transplantation donors. HLA typing was made serologically using standard lymphocytotoxicity techniques. HLA A29, B51, CW5, DR14, DR16, and DQ1 were the most common antigens in the control group. Frequency of HLA B13, CW7, B8, DR7, DR17 and DQ2 was higher in CD patients than in the control group (p |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0041-4301 2791-6421 |
| Relation: | https://turkjpediatr.org/article/view/2482; https://doaj.org/toc/0041-4301; https://doaj.org/toc/2791-6421 |
| Access URL: | https://doaj.org/article/eaba13c8a69740da8871404867163a9b |
| Accession Number: | edsdoj.ba13c8a69740da8871404867163a9b |
| Database: | Directory of Open Access Journals |
| ISSN: | 00414301 27916421 |
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| Published in: | The Turkish Journal of Pediatrics |
| Language: | English |