Bibliographic Details
| Title: |
Active Continuous-Flow Micromixer Using an External Braille Pin Actuator Array |
| Authors: |
Junichi Miwa, Roland Zengerle, Felix von Stetten, Yawar Abbas |
| Source: |
Micromachines, Vol 4, Iss 1, Pp 80-89 (2013) |
| Publisher Information: |
MDPI AG, 2013. |
| Publication Year: |
2013 |
| Collection: |
LCC:Mechanical engineering and machinery |
| Subject Terms: |
active micromixer, continuous-flow, chaotic advection, channel wall deflection, PDMS chip, cell sample dilution, microfluidic Braille pin actuated platform, Mechanical engineering and machinery, TJ1-1570 |
| More Details: |
We present a continuous-flow active micromixer based on channel-wall deflection in a polydimethylsiloxane (PDMS) chip for volume flows in the range up to 2 μL s−1 which is intended as a novel unit operation for the microfluidic Braille pin actuated platform. The chip design comprises a main microchannel connected to a series of side channels with dead ends aligned on the Braille pins. Computer-controlled deflection of the side-channel walls induces chaotic advection in the main-channel, which substantially accelerates mixing in low-Reynolds number flow. Sufficient mixing (mixing index MI below 0.1) of volume flows up to 0.5 μL s−1 could be achieved within residence times ~500 ms in the micromixer. As an application, continuous dilution of a yeast cell sample by a ratio down to 1:10 was successfully demonstrated. The mixer is intended to serve as a component of bio-analytical devices or as a unit operation in the microfluidic Braille pin actuated platform. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2072-666X |
| Relation: |
http://www.mdpi.com/2072-666X/4/1/80; https://doaj.org/toc/2072-666X |
| DOI: |
10.3390/mi4010080 |
| Access URL: |
https://doaj.org/article/eb9ebcaa1d674e66a6a0eda285c93363 |
| Accession Number: |
edsdoj.b9ebcaa1d674e66a6a0eda285c93363 |
| Database: |
Directory of Open Access Journals |
