Bibliographic Details
| Title: |
A controlled clinical study on efficacy and safety of periocular triamcinolone acetonide injection for treating ocular myasthenia gravis |
| Authors: |
Minghua Shi, Zhuneng Lu, Aijiao Qin, Jing Cheng, Simin Chen, Yiqiao Xing |
| Source: |
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-10 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Ophthalmology |
| Subject Terms: |
Ocular myasthenia gravis, Ptosis, Ophthalmoplegia, Peribulbar injection, Triamcinolone acetonide, Ophthalmology, RE1-994 |
| More Details: |
Abstract Objective To evaluate the efficacy and safety of peribulbar triamcinolone acetonide injection for treating ocular myasthenia gravis (OMG), with a comparison of traditional oral drug therapy. Methods A total of 22 patients with OMG who received periocular triamcinolone acetonide injection (initially 20 mg weekly, then once per month later if symptoms were improved) from July 2019 to July 2022 were evaluated by a comparison of symptom degree before and after treatment. Adverse reactions were also monitored during the period of treatment. The period of follow-up was more than 6 months. Additionally, a comparison of the treatment efficacy between this periocular injection and traditional oral administration was performed in OMG patients. Results After 4 weeks of treatment, the degree of ptosis in OMG patients decreased to -3.00 ± 0.69, compared to the value (-0.86 ± 1.32) before treatment. The degree of ophthalmoplegia also decreased from 3.12 ± 0.72 to 0.86 ± 0.88 (P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2415 |
| Relation: |
https://doaj.org/toc/1471-2415 |
| DOI: |
10.1186/s12886-024-03313-z |
| Access URL: |
https://doaj.org/article/b94a726905ad4e52ade9d6d0d0fff5bc |
| Accession Number: |
edsdoj.b94a726905ad4e52ade9d6d0d0fff5bc |
| Database: |
Directory of Open Access Journals |
