Bibliographic Details
| Title: |
Anaphylactic Reaction to Pemetrexed: A Case Report |
| Authors: |
Heloise Capelle, Joelle Birnbaum, Pascale Tomasini, Céline Tummino, Marion Gouitaa, Nathalie Ausias, Denis Charpin, Fabrice Barlesi, Marc Montana |
| Source: |
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 2 (2014) |
| Publisher Information: |
Frontiers Media S.A., 2014. |
| Publication Year: |
2014 |
| Collection: |
LCC:Therapeutics. Pharmacology
LCC:Pharmacy and materia medica |
| Subject Terms: |
Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441 |
| More Details: |
Pemetrexed is approved to treat non-small cell lung cancer and has an overall favorable toxicity profile. We describe a 58-year-old man who developped an anaphylactic shock within few minutes from the beginning of pemetrexed perfusion. Pemetrexed was discontinued and the patient’s symptoms gradually resolved with administration of symptomatic treatment. Serum tryptase level remained normal and intra dermal skin tests were negative eventhough a nonspecific papule was noted. This case suggests that caution should be exercised when prescribing pemetrexed and clinicians must be warranted for the possibility of serious adverse events associated with pemetrexed use. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1482-1826 |
| Relation: |
https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/21453; https://doaj.org/toc/1482-1826 |
| DOI: |
10.18433/J32C8D |
| Access URL: |
https://doaj.org/article/ab7f921a790d4d6993bb4ae494607f4e |
| Accession Number: |
edsdoj.b7f921a790d4d6993bb4ae494607f4e |
| Database: |
Directory of Open Access Journals |
