Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex

Bibliographic Details
Title: Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
Authors: Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Source: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Publisher Information: Nature Portfolio, 2022.
Publication Year: 2022
Collection: LCC:Science
Subject Terms: Science
More Details: HNRNPU is an RNA splicing protein associated with brain disorders such as early onset seizures. Here they show that HNRNPU functions to maintain neural progenitors and their progeny by regulating splicing of key neuronal genes.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-022-31752-z
Access URL: https://doaj.org/article/b79fbbfd33ea4996851afbb74dc44821
Accession Number: edsdoj.b79fbbfd33ea4996851afbb74dc44821
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-022-31752-z
Published in:Nature Communications
Language:English