Bibliographic Details
| Title: |
Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development |
| Authors: |
Arianna Pocaterra, Gloria Scattolin, Patrizia Romani, Cindy Ament, Silvia Ribback, Xin Chen, Matthias Evert, Diego F. Calvisi, Sirio Dupont |
| Source: |
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
Biology (General), QH301-705.5 |
| More Details: |
Pocaterra et al. demonstrate that Fascin1 F-actin bundling protein sustains YAP activation in the tumour environment in response to extracellular matrix mechanical cues. This study highlights Fascin1 as a potential clinical target in intrahepatic cholangiocarcinoma development. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-021-02286-9 |
| Access URL: |
https://doaj.org/article/b7806795bac144798bc500c28e43add1 |
| Accession Number: |
edsdoj.b7806795bac144798bc500c28e43add1 |
| Database: |
Directory of Open Access Journals |
