Features of optical coherence tomography angiography in age-related macular degeneration with residual fluid after three loading doses of aflibercept
| Title: | Features of optical coherence tomography angiography in age-related macular degeneration with residual fluid after three loading doses of aflibercept |
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| Authors: | Yong-Yeon Song, Hyun-Je Seong, Jung-Tae Kim, Sung-Chul Lee, Min-Woo Lee |
| Source: | Eye and Vision, Vol 11, Iss 1, Pp 1-8 (2024) |
| Publisher Information: | BMC, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Ophthalmology |
| Subject Terms: | Age-related macular degeneration, Aflibercept, Optical coherence tomography angiography, Ophthalmology, RE1-994 |
| More Details: | Abstract Background To identify the macular neovascularization (MNV) features in exudative age-related macular degeneration (AMD) patients who exhibited residual fluid after receiving three loading doses of aflibercept. Methods Patients were classified into two groups: Group 1, which did not exhibit intraretinal fluid (IRF) and subretinal fluid (SRF), and Group 2, which did exhibit IRF and/or SRF. Optical coherence tomography angiography (OCTA) features were assessed and compared between the groups. Results A total of 101 eyes were enrolled; 65 for Group 1 and 36 for Group 2. No significant differences were found in baseline MNV size (2.94 ± 2.51 µm2 vs. 2.22 ± 2.26 µm2, P = 0.178) or vessel density (47.1 ± 15.4 % vs. 41.3 ± 10.5%, P = 0.052) between Groups 1 and 2. There were significant differences in the presence of loops (52.3% vs. 75%, P = 0.026) and peripheral arcades (29.2% vs. 55.6%, P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2326-0254 53349679 |
| Relation: | https://doaj.org/toc/2326-0254 |
| DOI: | 10.1186/s40662-023-00372-z |
| Access URL: | https://doaj.org/article/ab649200a533496798b39e2057418c7b |
| Accession Number: | edsdoj.b649200a533496798b39e2057418c7b |
| Database: | Directory of Open Access Journals |
| ISSN: | 23260254 53349679 |
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| DOI: | 10.1186/s40662-023-00372-z |
| Published in: | Eye and Vision |
| Language: | English |