Characteristics of Patients with Acute Flaccid Myelitis, United States, 2015–2018
| Title: | Characteristics of Patients with Acute Flaccid Myelitis, United States, 2015–2018 |
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| Authors: | Nilay McLaren, Adriana Lopez, Sarah Kidd, John X. Zhang, W. Allan Nix, Ruth Link-Gelles, Adria Lee, Janell A. Routh |
| Source: | Emerging Infectious Diseases, Vol 26, Iss 2, Pp 212-219 (2020) |
| Publisher Information: | Centers for Disease Control and Prevention, 2020. |
| Publication Year: | 2020 |
| Collection: | LCC:Medicine LCC:Infectious and parasitic diseases |
| Subject Terms: | myelitis, paralysis, enterovirus, pediatrics, acute flaccid myelitis, United States, Medicine, Infectious and parasitic diseases, RC109-216 |
| More Details: | Observed peaks of acute flaccid myelitis (AFM) cases have occurred biennially since 2014 in the United States. We aimed to determine if AFM etiology differed between peak and nonpeak years, considering that clinical features of AFM differ by virus etiology. We compared clinical and laboratory characteristics of AFM cases that occurred during peak (2016 and 2018, n = 366) and nonpeak (2015 and 2017, n = 50) years. AFM patients in peak years were younger (5.2 years) than those in nonpeak years (8.3 years). A higher percentage of patients in peak years than nonpeak years had pleocytosis (86% vs. 60%), upper extremity involvement (33% vs. 16%), and an illness preceding limb weakness (90% vs. 62%) and were positive for enterovirus or rhinovirus RNA (38% vs. 16%). Enterovirus D68 infection was associated with AFM only in peak years. Our findings suggest AFM etiology differs between peak and nonpeak years. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/26/2/19-1453_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid2602.191453 |
| Access URL: | https://doaj.org/article/eb64915354bd4bb483ecacdc7b8f24df |
| Accession Number: | edsdoj.b64915354bd4bb483ecacdc7b8f24df |
| Database: | Directory of Open Access Journals |
| ISSN: | 10806040 10806059 |
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| DOI: | 10.3201/eid2602.191453 |
| Published in: | Emerging Infectious Diseases |
| Language: | English |