Bibliographic Details
| Title: |
Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest |
| Authors: |
Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang |
| Source: |
Resuscitation Plus, Vol 22, Iss , Pp 100881- (2025) |
| Publisher Information: |
Elsevier, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Specialties of internal medicine |
| Subject Terms: |
Acute kidney injury, End-stage renal disease, Out-of-hospital cardiac arrest, Renal function, Specialties of internal medicine, RC581-951 |
| More Details: |
Background: Comprehensive studies about renal-function changes in the context of out-of-hospital cardiac arrest (OHCA) have been lacking. Therefore, we investigated the impact of renal function on clinical outcomes among patients with OHCA. Method: This retrospective cohort study enrolled consecutive patients with OHCA between June 2017 and December 2021. Acute kidney injury (AKI) was defined based on the “Kidney Disease: Improving Global Outcomes (KDIGO)” guidelines. AKI recovery was defined as a decrease in serum creatinine below the level determined in the definition of AKI. Clinical outcomes included neurological outcomes and all-cause mortality. Result: A total of 258 patients were enrolled, including 35 patients with underlying end-stage renal disease (ESRD). Among patients without ESRD, 82.5% developed AKI, of which 31.0% achieved AKI recovery, while 61.0% were discharged with impaired renal function. Multivariable analysis using regression models revealed that unfavorable neurological outcomes at discharge and higher mortality at 2 years were associated with AKI (odds ratio [OR] 7.684, 95% confidence interval (CI) 2.683–22.010, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2666-5204 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2666520425000189; https://doaj.org/toc/2666-5204 |
| DOI: |
10.1016/j.resplu.2025.100881 |
| Access URL: |
https://doaj.org/article/b61cee27f1554bab8f74d295d1d72ed5 |
| Accession Number: |
edsdoj.b61cee27f1554bab8f74d295d1d72ed5 |
| Database: |
Directory of Open Access Journals |
