Bibliographic Details
Title: |
SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung |
Authors: |
Nanda Kishore Routhu, Narayanaiah Cheedarla, Venkata Satish Bollimpelli, Sailaja Gangadhara, Venkata Viswanadh Edara, Lilin Lai, Anusmita Sahoo, Ayalnesh Shiferaw, Tiffany M. Styles, Katharine Floyd, Stephanie Fischinger, Caroline Atyeo, Sally A. Shin, Sanjeev Gumber, Shannon Kirejczyk, Kenneth H. Dinnon, Pei-Yong Shi, Vineet D. Menachery, Mark Tomai, Christopher B. Fox, Galit Alter, Thomas H. Vanderford, Lisa Gralinski, Mehul S. Suthar, Rama Rao Amara |
Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
Publisher Information: |
Nature Portfolio, 2021. |
Publication Year: |
2021 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Efficient vaccines for SARS-CoV-2 are needed. Here, the authors show that a trimeric form of the receptor-binding domain of SARS-CoV-2 spike adjuvanted with alum-3M-052 protects non-human primates from disease and inhibits infection. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-021-23942-y |
Access URL: |
https://doaj.org/article/eb5e727593c442beadc6bb289092f047 |
Accession Number: |
edsdoj.b5e727593c442beadc6bb289092f047 |
Database: |
Directory of Open Access Journals |