Occupational exposure to flame retardants following production replacement and their effect on thyroid function indicators

Bibliographic Details
Title: Occupational exposure to flame retardants following production replacement and their effect on thyroid function indicators
Authors: Ling Meng, Tingting Guo, Yizhi Liu, Han Wu, Kang An, Xizhu Xu, Yuancheng Li
Source: Emerging Contaminants, Vol 11, Iss 2, Pp 100476- (2025)
Publisher Information: KeAi Communications Co., Ltd., 2025.
Publication Year: 2025
Collection: LCC:Environmental pollution
Subject Terms: Brominated flame retardants, Organophosphate ester flame retardants, Occupational exposure, Thyroid function indicators, Environmental pollution, TD172-193.5
More Details: With the ban of commercial Penta-BDEs, Octa-BDEs, and Deca-BDEs, many manufacturers have been transition to the production of novel brominated flame retardants (NBFRs), organophosphate ester flame retardants (OPFRs), and other alternatives. In this study, we recruited 165 employees with typical occupational exposure from a flame retardants (FRs) production plant in Laizhou Bay, which is the main FRs production area in China, to analyze the internal exposure characteristics of FRs and their potential impacts on thyroid function during the historical production and replacement process. The results showed that the detection frequencies of only triphenyl phosphate (TPHP), BDE-138 and BDE-197 (82.4 %, 61.2 % and 60.6 %, respectively) exceeded 60 % among the 34 compounds of interest, while the median concentrations of BDE-138 and BDE-197 were much higher than TPHP (medians of 103.6, 60.6 and 20.5 ng/g lw, respectively). In addition, the concentrations of these compounds in exposed group are higher than those in the control group (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2405-6650
Relation: http://www.sciencedirect.com/science/article/pii/S2405665025000101; https://doaj.org/toc/2405-6650
DOI: 10.1016/j.emcon.2025.100476
Access URL: https://doaj.org/article/b5897efdbebe4b83b6b2fc8e64f79d45
Accession Number: edsdoj.b5897efdbebe4b83b6b2fc8e64f79d45
Database: Directory of Open Access Journals
More Details
ISSN:24056650
DOI:10.1016/j.emcon.2025.100476
Published in:Emerging Contaminants
Language:English