Bibliographic Details
| Title: |
The Prevalence of Liver Cytolysis in Children with Helicobacter pylori Infection |
| Authors: |
Ancuta Lupu, Ingrith Crenguta Miron, Anca Lavinia Cianga, Andrei Tudor Cernomaz, Vasile Valeriu Lupu, Cristina Gavrilovici, Iuliana Magdalena Stârcea, Elena Tarca, Dragos Catalin Ghica, Silvia Fotea |
| Source: |
Children, Vol 9, Iss 10, p 1498 (2022) |
| Publisher Information: |
MDPI AG, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Pediatrics |
| Subject Terms: |
liver cytolysis, Helicobacter pylori, children, transaminases, Pediatrics, RJ1-570 |
| More Details: |
(1) Background: The relationship between Helicobacter pylori (H. pylori) infection and liver disease has been discussed for many years, but the association between the infection and liver cytolysis in children has been insufficiently explored. In our study, we evaluate this relationship in a pediatric population from the northeast of Romania. (2) Methods: A retrospective study of children with H. pylori infection and liver cytolysis was conducted on a group of 1757 children, admitted to a pediatric gastroenterology regional center in northeast Romania over 3 years. (3) Results: Liver cytolysis syndrome was present in 112 children of both sexes. Of the 112 children, 20 children (17.9%) also had H. pylori infection. In the statistical analysis, we noted a significant association between liver cytolysis syndrome and H. pylori infection (χ2; p < 0.001). (4) Conclusions: This relationship requires further in-depth studies that also consider certain parameters that may influence the results of these correlations. In addition, we point out the need for further analyses evaluating, in terms of the histopathological changes in each liver disease, the efficacy of H. pylori eradication. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2227-9067 |
| Relation: |
https://www.mdpi.com/2227-9067/9/10/1498; https://doaj.org/toc/2227-9067 |
| DOI: |
10.3390/children9101498 |
| Access URL: |
https://doaj.org/article/b5885ca588a54e0b97129a7bcb60350e |
| Accession Number: |
edsdoj.b5885ca588a54e0b97129a7bcb60350e |
| Database: |
Directory of Open Access Journals |
