Bibliographic Details
| Title: |
A Case report: Synovial sarcoma of the mediastinum in an 18-year-old teenager |
| Authors: |
Yan Liu, Manman Cui, Xiuzhi Zhou, Duchang Zhai, Mingyu Qin, Guohua Fan, Wu Cai |
| Source: |
Frontiers in Oncology, Vol 14 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
synovial sarcoma, mediastinum, mesenchymal cell, chest imaging, oncology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Synovial sarcomas (SSs) are a rare group of malignant tumors originating from pluripotential mesenchymal cells, which commonly occur as the primary tumor in the soft tissues near the articular surface, tendons, and articular synovium. Herein, we report a rare case of mediastinal SS in an 18-year-old teenager who initially presented with cough as the primary symptom. In this case, plain chest CT and contrast-enhanced CT clearly revealed the lesion presenting as a round-like and uneven density mass in the mediastinum with heterogeneous enhancement, which compressed the trachea and invaded the adjacent vessels. Based on the results of immunohistochemistry and fluorescence in situ hybridization (FISH), combined with the differential diagnosis with other types of tumors in the mediastinum on imaging, we were able to diagnose the tumor as an SS located in the mediastinum. Subsequent resection of the lesion coupled with chemotherapy and immunotherapy led to an improvement in the patient’s symptoms. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2234-943X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fonc.2024.1288213/full; https://doaj.org/toc/2234-943X |
| DOI: |
10.3389/fonc.2024.1288213 |
| Access URL: |
https://doaj.org/article/b40fcc06f15d426597a974d859e55db1 |
| Accession Number: |
edsdoj.b40fcc06f15d426597a974d859e55db1 |
| Database: |
Directory of Open Access Journals |
