Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism

Bibliographic Details
Title: Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism
Authors: Xiaodi Tang, Shenghai Chang, Qinghua Luo, Zhengyu Zhang, Wen Qiao, Caihuang Xu, Changbin Zhang, Yang Niu, Wenxian Yang, Ting Wang, Zhibo Zhang, Xiaofeng Zhu, Xiawei Wei, Changjiang Dong, Xing Zhang, Haohao Dong
Source: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Publisher Information: Nature Portfolio, 2019.
Publication Year: 2019
Collection: LCC:Science
Subject Terms: Science
More Details: Seven lipopolysaccharide (LPS) transport proteins (LptBFGCADE) mediate the transport of LPS from the inner to the outer membrane of Gram-negative bacteria. Here the authors provide mechanistic insights into LPS recognition and transportation by determining the cryo-EM structures of the inner membrane complex LptB2FGC bound to either LPS or AMP-PNP.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-019-11977-1
Access URL: https://doaj.org/article/b2966fc978dc4035a64b64637481ce2f
Accession Number: edsdoj.b2966fc978dc4035a64b64637481ce2f
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-019-11977-1
Published in:Nature Communications
Language:English