Hyponatremia in Tuberculosis Meningitis: Navigating the Diagnostic Challenges of Cerebral Salt Wasting – A Case Report

Bibliographic Details
Title: Hyponatremia in Tuberculosis Meningitis: Navigating the Diagnostic Challenges of Cerebral Salt Wasting – A Case Report
Authors: Yousra Nasir Siddiqui
Source: Journal of Bahria University Medical and Dental College, Vol 14, Iss 01, Pp 93-95 (2024)
Publisher Information: Bahria Univerisy Health Sciences, Campus Karachi, 2024.
Publication Year: 2024
Collection: LCC:Dentistry
LCC:Medicine (General)
Subject Terms: siadh, tuberculous meningitis, cerebral salt wasting, hyponatremia, fludrocortisone, Dentistry, RK1-715, Medicine (General), R5-920
More Details: A 10 year old female presented with fever, headache and vomiting since four days. Her laboratory workup revealed low serum sodium, serum osmolality. CT scan of the brain was unremarkable, while on CSF examination, protein, and total leukocyte count (predominantly lymphocytes) were increased. CSF cultures were negative, however, GeneXpert detected rifampicin resistant mycobacterium tuberculosis. Due to her high urine output and hyponatremia with sodium of 128 mEq/l, fluid restriction was attempted in order to rule out the diagnosis of SIADH, but the patient was unresponsive to it. Thus, the patient was diagnosed with tuberculous meningitis after further workup, followed by cerebral salt wasting. She was started on anti-tuberculous therapy (ATT), 3% hypertonic saline and flucrocortisone, to which she was responsive, and eventually discharged.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2220-7562
2617-9482
Relation: https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/1358; https://doaj.org/toc/2220-7562; https://doaj.org/toc/2617-9482
DOI: 10.51985/JBUMDC2023270
Access URL: https://doaj.org/article/b27e7cfdc8334312ae4d69f4d9e5722e
Accession Number: edsdoj.b27e7cfdc8334312ae4d69f4d9e5722e
Database: Directory of Open Access Journals
More Details
ISSN:22207562
26179482
DOI:10.51985/JBUMDC2023270
Published in:Journal of Bahria University Medical and Dental College
Language:English