Full Text from JSTOR Nightshift work job exposure matrices and urinary 6-sulfatoxymelatonin levels among healthy Chinese women
| Title: | Nightshift work job exposure matrices and urinary 6-sulfatoxymelatonin levels among healthy Chinese women |
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| Authors: | Bu-Tian Ji, Yu-Tang Gao, Xiao-Ou Shu, Gong Yang, Kai Yu, Shou-Zheng Xue, Hong-Lan Li, Linda M Liao, Aaron Blair, Nathaniel Rothman, Wei Zheng, Wong-Ho Chow |
| Source: | Scandinavian Journal of Work, Environment & Health, Vol 38, Iss 6, Pp 553-559 (2012) |
| Publisher Information: | Nordic Association of Occupational Safety and Health (NOROSH), 2012. |
| Publication Year: | 2012 |
| Collection: | LCC:Public aspects of medicine |
| Subject Terms: | cancer, china, shift work, melatonin, woman, night shift, job exposure matrix, nighttime work, urinary 6-sulfatoxymelatonin, amt6s, urine sample, Public aspects of medicine, RA1-1270 |
| More Details: | OBJECTIVE: Six-sulfatoxymelatonin (aMT6s) is a primary urinary metabolite of melatonin. We examined the association between aMT6s levels and shift work estimated by a job exposure matrix (JEM) among healthy participants of the Shanghai Women’s Health Study. METHODS: Creatinine-adjusted aMT6s levels were measured in the urine samples of 300 women and related to JEM shift work categories. RESULTS: Adjusted geometric means of aMT6s levels from urine samples collected before 08:00 hours were lower among persons holding nighttime shift work jobs. The adjusted aMT6s levels (ng/mg creatinine) were 8.36 [95% confidence intervals (95% CI) 4.47–15.6], 6.37 (95% CI 3.53–11.5), 6.20 (95% CI 3.33–11.5), 3.81 (95% CI 2.02–7.19), and 3.70 (95% CI 1.92–7.11) from the lowest (never held a shift work job) to the highest (current job likely involved all-night shift work) shift work JEM scores (P=0.05). CONCLUSION: Our results indicate that nightshift work JEM scores were significantly and inversely associated with aMT6s levels in early morning spot urine samples collected between 07:00–08:00 hours. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0355-3140 1795-990X |
| Relation: | https://www.sjweh.fi/show_abstract.php?abstract_id=3322; https://doaj.org/toc/0355-3140; https://doaj.org/toc/1795-990X |
| DOI: | 10.5271/sjweh.3322 |
| Access URL: | https://doaj.org/article/eb25baba6c9f4fc4891b93c66f7769c5 |
| Accession Number: | edsdoj.b25baba6c9f4fc4891b93c66f7769c5 |
| Database: | Directory of Open Access Journals |
| ISSN: | 03553140 1795990X |
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| DOI: | 10.5271/sjweh.3322 |
| Published in: | Scandinavian Journal of Work, Environment & Health |
| Language: | English |