Hyperkalemia: Prevalence, Predictors and Emerging Treatments
| Title: | Hyperkalemia: Prevalence, Predictors and Emerging Treatments |
|---|---|
| Authors: | Natasha L. Larivée, Jacob B. Michaud, Keigan M. More, Jo-Anne Wilson, Karthik K. Tennankore |
| Source: | Cardiology and Therapy, Vol 12, Iss 1, Pp 35-63 (2022) |
| Publisher Information: | Adis, Springer Healthcare, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: | Hyperkalemia, Potassium binder, Patiromer, Sodium zirconium cyclosilicate, Sodium polystyrene sulfonate, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: | Abstract It is well established that an elevated potassium level (hyperkalemia) is associated with a risk of adverse events including morbidity, mortality and healthcare system cost. Hyperkalemia is commonly encountered in many chronic conditions including kidney disease, diabetes and heart failure. Furthermore, hyperkalemia may result from the use of renin-angiotensin-aldosterone system inhibitors (RAASi), which are disease-modifying treatments for these conditions. Therefore, balancing the benefits of optimizing treatment with RAASi while mitigating hyperkalemia is crucial to ensure patients are optimally treated. In this review, we will briefly discuss the definition, causes, epidemiology and consequences of hyperkalemia. The majority of the review will be focused on management of hyperkalemia in the acute and chronic setting, emphasizing contemporary approaches and evolving data on the relevance of dietary restriction and the use of novel potassium binders. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2193-8261 2193-6544 |
| Relation: | https://doaj.org/toc/2193-8261; https://doaj.org/toc/2193-6544 |
| DOI: | 10.1007/s40119-022-00289-z |
| Access URL: | https://doaj.org/article/b127f57662f74115acab999a47bd13b6 |
| Accession Number: | edsdoj.b127f57662f74115acab999a47bd13b6 |
| Database: | Directory of Open Access Journals |
| ISSN: | 21938261 21936544 |
|---|---|
| DOI: | 10.1007/s40119-022-00289-z |
| Published in: | Cardiology and Therapy |
| Language: | English |