Bibliographic Details
| Title: |
Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer |
| Authors: |
Yiting Lim, Sonali Arora, Samantha L. Schuster, Lukas Corey, Matthew Fitzgibbon, Cynthia L. Wladyka, Xiaoying Wu, Ilsa M. Coleman, Jeffrey J. Delrow, Eva Corey, Lawrence D. True, Peter S. Nelson, Gavin Ha, Andrew C. Hsieh |
| Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Mutations in 5’ untranslated regions (UTRs) have a functional role in gene expression in cancer. Here, the authors develop a sequencing-based high throughput functional assay named PLUMAGE and show the effects of these mutations on gene expression and their association with clinical outcomes in prostate cancer. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-24445-6 |
| Access URL: |
https://doaj.org/article/b09e659db3294cf0bec903efcd4f8344 |
| Accession Number: |
edsdoj.b09e659db3294cf0bec903efcd4f8344 |
| Database: |
Directory of Open Access Journals |
