Morphologic and Genetic Characterization of Ilheus Virus, a Potential Emergent Flavivirus in the Americas

Bibliographic Details
Title: Morphologic and Genetic Characterization of Ilheus Virus, a Potential Emergent Flavivirus in the Americas
Authors: Jessica A. Plante, Kenneth S. Plante, Vsevolod L. Popov, Divya P. Shinde, Steven G. Widen, Michaela Buenemann, Mauricio L. Nogueira, Nikos Vasilakis
Source: Viruses, Vol 15, Iss 1, p 195 (2023)
Publisher Information: MDPI AG, 2023.
Publication Year: 2023
Collection: LCC:Microbiology
Subject Terms: Ilheus virus, ILHV, flavivirus, morphologic and genetic characterization, Microbiology, QR1-502
More Details: Ilheus virus (ILHV) is a mosquito-borne flavivirus circulating throughout Central and South America and the Caribbean. It has been detected in several mosquito genera including Aedes and Culex, and birds are thought to be its primary amplifying and reservoir host. Here, we describe the genomic and morphologic characterization of ten ILHV strains. Our analyses revealed a high conservation of both the 5′- and 3′-untranslated regions but considerable divergence within the open reading frame. We also showed that ILHV displays a typical flavivirus structural and genomic organization. Our work lays the foundation for subsequent ILHV studies to better understand its transmission cycles, pathogenicity, and emergence potential.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1999-4915
Relation: https://www.mdpi.com/1999-4915/15/1/195; https://doaj.org/toc/1999-4915
DOI: 10.3390/v15010195
Access URL: https://doaj.org/article/b0705f552d5b40bbba0d0315644771c2
Accession Number: edsdoj.b0705f552d5b40bbba0d0315644771c2
Database: Directory of Open Access Journals
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More Details
ISSN:19994915
DOI:10.3390/v15010195
Published in:Viruses
Language:English