Bibliographic Details
Title: |
Morphologic and Genetic Characterization of Ilheus Virus, a Potential Emergent Flavivirus in the Americas |
Authors: |
Jessica A. Plante, Kenneth S. Plante, Vsevolod L. Popov, Divya P. Shinde, Steven G. Widen, Michaela Buenemann, Mauricio L. Nogueira, Nikos Vasilakis |
Source: |
Viruses, Vol 15, Iss 1, p 195 (2023) |
Publisher Information: |
MDPI AG, 2023. |
Publication Year: |
2023 |
Collection: |
LCC:Microbiology |
Subject Terms: |
Ilheus virus, ILHV, flavivirus, morphologic and genetic characterization, Microbiology, QR1-502 |
More Details: |
Ilheus virus (ILHV) is a mosquito-borne flavivirus circulating throughout Central and South America and the Caribbean. It has been detected in several mosquito genera including Aedes and Culex, and birds are thought to be its primary amplifying and reservoir host. Here, we describe the genomic and morphologic characterization of ten ILHV strains. Our analyses revealed a high conservation of both the 5′- and 3′-untranslated regions but considerable divergence within the open reading frame. We also showed that ILHV displays a typical flavivirus structural and genomic organization. Our work lays the foundation for subsequent ILHV studies to better understand its transmission cycles, pathogenicity, and emergence potential. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1999-4915 |
Relation: |
https://www.mdpi.com/1999-4915/15/1/195; https://doaj.org/toc/1999-4915 |
DOI: |
10.3390/v15010195 |
Access URL: |
https://doaj.org/article/b0705f552d5b40bbba0d0315644771c2 |
Accession Number: |
edsdoj.b0705f552d5b40bbba0d0315644771c2 |
Database: |
Directory of Open Access Journals |
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