Academic Journal
Reference Interval of Thyroid Stimulating Hormone and free Tetra-iodothyronine in Healthy Pregnant Women of Quetta, Baluchistan
| Title: | Reference Interval of Thyroid Stimulating Hormone and free Tetra-iodothyronine in Healthy Pregnant Women of Quetta, Baluchistan |
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| Authors: | Azadi Khan, Naveed Asif, Razaullah ., Taimoor Ashraf Khan, Asma Khan, Saima Shakil Malik |
| Source: | Pakistan Armed Forces Medical Journal, Vol 72, Iss 6 (2022) |
| Publisher Information: | Army Medical College Rawalpindi, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine LCC:Medicine (General) |
| Subject Terms: | Reference interval, Pregnancy, Trimester, Thyroid stimulating hormone, Medicine, Medicine (General), R5-920 |
| More Details: | Objective: To establish the reference intervals of thyroid stimulating hormone and free Tetraiodothyronine in healthy pregnant women of Quetta, Baluchistan. Study Design: Cross-sectional study. Study Setting and Duration: Combined Military Hospital, Quetta Pakistan, at Jun 2018 to Jun 2019. Methodology: Consecutive blood samples of healthy pregnant women (in all three trimesters) were taken to analyse thyroid stimulating hormone and free Tetra-iodothyronine by electrochemiluminescence immunoassay. For all three trimesters, the 5th and 95th percentiles were taken as reference intervals of thyroid stimulating hormone and free Tetraiodothyronine. Results: A total of 388 blood samples were taken. Of these, 136 samples were from the first trimester. The mean age of the study population was 25.1±3.7 years in the first trimester, 26.7±4.5 years in the second trimester, and in the third trimester, it was 26.8±4.8 years. The reference interval for thyroid stimulating hormone in the first trimester was 0.6-3.3 uIU//ml, while it was 0.6-3.8uIU/ml and 0.6- 2.7uIU//ml during the second and third trimesters, respectively. Similarly, in the first-trimester reference interval for free Tetraiodothyronine was 9.8-18.0pmol/l. The values of free Tetraiodothyronine in the second and third trimesters were 10.4-20.1pmol/l and 11.0-20.9pmol/l, respectively. Conclusion: All laboratories should establish reference intervals for thyroid stimulating hormone (TSH) to avoid misdiagnosing thyroid disorders during pregnancy. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0030-9648 2411-8842 |
| Relation: | https://pafmj.org/index.php/PAFMJ/article/view/4729; https://doaj.org/toc/0030-9648; https://doaj.org/toc/2411-8842 |
| DOI: | 10.51253/pafmj.v72i6.4729 |
| Access URL: | https://doaj.org/article/cb01a7b50d394fd4a385fc4893922c34 |
| Accession Number: | edsdoj.b01a7b50d394fd4a385fc4893922c34 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 00309648 24118842 |
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| DOI: | 10.51253/pafmj.v72i6.4729 |
| Published in: | Pakistan Armed Forces Medical Journal |
| Language: | English |