Bibliographic Details
Title: |
Genome-wide compendium and functional assessment of in vivo heart enhancers |
Authors: |
Diane E. Dickel, Iros Barozzi, Yiwen Zhu, Yoko Fukuda-Yuzawa, Marco Osterwalder, Brandon J. Mannion, Dalit May, Cailyn H. Spurrell, Ingrid Plajzer-Frick, Catherine S. Pickle, Elizabeth Lee, Tyler H. Garvin, Momoe Kato, Jennifer A. Akiyama, Veena Afzal, Ah Young Lee, David U. Gorkin, Bing Ren, Edward M. Rubin, Axel Visel, Len A. Pennacchio |
Source: |
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
Publisher Information: |
Nature Portfolio, 2016. |
Publication Year: |
2016 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Identification of non-coding variants has outstripped our ability to annotate and interpret them. Dickel et al. present a compendium of over 80,000 putative human heart enhancers and demonstrate that two conserved enhancers are required for proper cardiac function in mice. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/ncomms12923 |
Access URL: |
https://doaj.org/article/b001d43a207246388e738ba39f9b2876 |
Accession Number: |
edsdoj.b001d43a207246388e738ba39f9b2876 |
Database: |
Directory of Open Access Journals |