The molecular, electrophysiological, and structural changes in the vestibular nucleus during vestibular compensation: a narrative review
| Title: | The molecular, electrophysiological, and structural changes in the vestibular nucleus during vestibular compensation: a narrative review |
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| Authors: | Pengjun Wang, Wen Lu, Yini Li, Haibo Shi, Shankai Yin |
| Source: | Journal of Bio-X Research, Vol 4, Iss 4, Pp 158-162 (2021) |
| Publisher Information: | American Association for the Advancement of Science (AAAS), 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Medicine LCC:Biology (General) |
| Subject Terms: | Medicine, Biology (General), QH301-705.5 |
| More Details: | Abstract. The vestibular system involves high-level sensory and cognitive processes, such as spatial perception, balance control, visual stability, and emotional control. Vestibular dysfunction can induce vertigo, blurred vision, postural imbalance, walking instability, and spatial discomfort, which causes serious damage to health. It has long been known that after peripheral vestibular lesion, vestibular dysfunction may spontaneously recover. This is known as vestibular compensation. However, at least 20% to 30% of patients with vestibular disorders cannot yield vestibular compensation and remain with vestibular dysfunction for the rest of their lives. The exploration of the biological characteristics and regulatory factors of the loss and reestablishment of vestibular function will establish a new understanding of the mechanism of vestibular compensation and provide new tools and strategies for promoting vestibular rehabilitation. We aim to comprehensively review the mechanism of vestibular compensation and discuss future directions in this field. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2096-5672 2577-3585 00000000 |
| Relation: | http://journals.lww.com/10.1097/JBR.0000000000000107; https://doaj.org/toc/2096-5672; https://doaj.org/toc/2577-3585 |
| DOI: | 10.1097/JBR.0000000000000107 |
| Access URL: | https://doaj.org/article/e9f7aee373b149c19816231ba75951f1 |
| Accession Number: | edsdoj.9f7aee373b149c19816231ba75951f1 |
| Database: | Directory of Open Access Journals |
| ISSN: | 20965672 25773585 00000000 |
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| DOI: | 10.1097/JBR.0000000000000107 |
| Published in: | Journal of Bio-X Research |
| Language: | English |