Bibliographic Details
| Title: |
Bone marrow plasma level of decorin may be associated with improved treatment outcomes in a subset of multiple myeloma patients |
| Authors: |
Shang-Yi Huang, Hsiu-Hsia Lin, Ming Yao, Jih-Luh Tang, Shang-Ju Wu, Wen-Chien Chou, Szu-Chun Hsu, Bor-Sheng Ko, Hwei-Fang Tien |
| Source: |
Journal of the Formosan Medical Association, Vol 121, Iss 3, Pp 643-651 (2022) |
| Publisher Information: |
Elsevier, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Medicine (General) |
| Subject Terms: |
Decorin, Extracellular matrix, Hepatocyte growth factor, Myeloma, Mesenchymal stem cell, Medicine (General), R5-920 |
| More Details: |
Background/purpose: Decorin is a small leucine-rich proteoglycan rich in extracellular matrix with potential antitumor activity. However, the role of decorin in hematological malignancies remains unclear, especially in the case of multiple myeloma (MM), a bone marrow (BM) stroma-dependent plasma cell neoplasm. Methods: We measured decorin levels in BM plasma samples from 270 patients with newly diagnosed MM (NDMM) using enzyme-linked immunosorbent assays. Results: Patients were divided into high decorin (H-DCN, > 18.99 ng/mL) and low decorin (L-DCN |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
0929-6646 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S0929664621002953; https://doaj.org/toc/0929-6646 |
| DOI: |
10.1016/j.jfma.2021.06.015 |
| Access URL: |
https://doaj.org/article/9e551f663ab6473fab50484f2afc7539 |
| Accession Number: |
edsdoj.9e551f663ab6473fab50484f2afc7539 |
| Database: |
Directory of Open Access Journals |
