Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus

Bibliographic Details
Title: Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus
Authors: C. David Owen, Louise E. Tailford, Serena Monaco, Tanja Šuligoj, Laura Vaux, Romane Lallement, Zahra Khedri, Hai Yu, Karine Lecointe, John Walshaw, Sandra Tribolo, Marc Horrex, Andrew Bell, Xi Chen, Gary L. Taylor, Ajit Varki, Jesus Angulo, Nathalie Juge
Source: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Publisher Information: Nature Portfolio, 2017.
Publication Year: 2017
Collection: LCC:Science
Subject Terms: Science
More Details: The mucus layer is an important physical niche within the gut which harbours a distinct microbial community. Here the authors show that specific carbohydrate-binding modules associated with bacterial carbohydrate-active enzymes are mucus adhesins that target regions of the distal colon rich in sialomucins.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-017-02109-8
Access URL: https://doaj.org/article/a9e2f73219e849be977339d14d916fea
Accession Number: edsdoj.9e2f73219e849be977339d14d916fea
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-017-02109-8
Published in:Nature Communications
Language:English