Cobimetinib‐induced 'dropped head syndrome' and subsequent disease management in an Erdheim‐Chester patient

Bibliographic Details
Title: Cobimetinib‐induced 'dropped head syndrome' and subsequent disease management in an Erdheim‐Chester patient
Authors: Amber C. King, Eli L. Diamond, Jennifer S. Orozco, Hannah R. Morse, Linda L. Ouyang, Heiko Schöder, Raajit K. Rampal
Source: Clinical Case Reports, Vol 7, Iss 10, Pp 1989-1993 (2019)
Publisher Information: Wiley, 2019.
Publication Year: 2019
Collection: LCC:Medicine
LCC:Medicine (General)
Subject Terms: Erdheim‐Chester disease, hematology, neurology, pharmacology, Medicine, Medicine (General), R5-920
More Details: Abstract Our rechallenge of cobimetinib in an Erdheim‐Chester Disease (ECD) patient for the rare adverse effect, “dropped head syndrome,” with a previously unexplored cobimetinib regimen was successful. Similar to other experiences with targeted agents in ECD, dosing of cobimetinib may vary to mitigate toxicity without impairing efficacy.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2050-0904
Relation: https://doaj.org/toc/2050-0904
DOI: 10.1002/ccr3.2297
Access URL: https://doaj.org/article/9e1e6f10b4fd4244b1452a2eef66da91
Accession Number: edsdoj.9e1e6f10b4fd4244b1452a2eef66da91
Database: Directory of Open Access Journals
More Details
ISSN:20500904
DOI:10.1002/ccr3.2297
Published in:Clinical Case Reports
Language:English