Regulation of Biological Functions at the Cell Interface by DNA Nanostructures

Bibliographic Details
Title: Regulation of Biological Functions at the Cell Interface by DNA Nanostructures
Authors: Yongjian Chen, Run Tian, Yingxu Shang, Qiao Jiang, Baoquan Ding
Source: Advanced NanoBiomed Research, Vol 2, Iss 2, Pp n/a-n/a (2022)
Publisher Information: Wiley-VCH, 2022.
Publication Year: 2022
Collection: LCC:Biotechnology
LCC:Medical technology
Subject Terms: cell interface, DNA nanostructures, regulation of cell behaviors and functions, self-assembly, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5
More Details: The control over specific biological functions of a single cell or between different cells is an exciting goal in the fields of biophysics and biochemistry. Besides the fast‐developed chemical biology methods, such as chemical labeling and gene editing, researchers are still seeking for efficient ways to manipulate cell behaviors. Over the past decades, self‐assembled DNA nanostructures have emerged as novel and versatile tools for the study of biological science. Featured with structural programmability, customized functionality, and marked biocompatibility, DNA nanostructures have been immensely exploited for a variety of fascinating biological applications including bioimaging and drug delivery. In addition, DNA nanostructures also hold great potential in the regulation of physiological functions at various biological interfaces. In this minireview, the recent progress of the regulation of biological processes and functions at cell interface using DNA nanostructures is summarized. Current challenges and opportunities in applying DNA nanoassemblies as tools for cell behavior manipulation are also briefly discussed.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2699-9307
Relation: https://doaj.org/toc/2699-9307
DOI: 10.1002/anbr.202100126
Access URL: https://doaj.org/article/9e109faf0f6a48a5a05ae1c7d714ee48
Accession Number: edsdoj.9e109faf0f6a48a5a05ae1c7d714ee48
Database: Directory of Open Access Journals
More Details
ISSN:26999307
DOI:10.1002/anbr.202100126
Published in:Advanced NanoBiomed Research
Language:English