Correlation between Carotid Arterial Calcium Score and Silent Cerebrovascular Lesions in Obstructive Sleep Apnea Patients: by Using Upper Airway CT and Brain MRI
| Title: | Correlation between Carotid Arterial Calcium Score and Silent Cerebrovascular Lesions in Obstructive Sleep Apnea Patients: by Using Upper Airway CT and Brain MRI |
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| Authors: | Moon Sung Kim, Eun-Ju Kang, Woo Yong Bae, Jong Kuk Kim, Chul Hoon Kim, Jae Hyung Choi, Sang-Hyun Kim, Dae Yeon Kim, Ki-Nam Lee |
| Source: | 대한영상의학회지, Vol 80, Iss 6, Pp 1214-1228 (2019) |
| Publisher Information: | The Korean Society of Radiology, 2019. |
| Publication Year: | 2019 |
| Collection: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| Subject Terms: | obstructive sleep apnea, carotid arteries, calcium, cerebrovascular disorders, cerebral ischemia, magnetic resonance imaging, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| More Details: | Purpose To investigate the relationship between carotid arterial calcium score (CarACS) and silent cerebrovascular lesions in patients with obstructive sleep apnea (OSA). Materials and Methods This study involved retrospective evaluation of 60 OSA patients who underwent both upper airway CT and brain MRI. Using polysomnography, several indicators, including apnea index (AI), were used to evaluate the relationship between OSA and silent cerebrovascular lesions. The CarACS was quantified on CT imaging using the modified Agatston method. Silent cerebrovascular lesions were evaluated on brain MRI by grading periventricular hyperintensity (PVH). Various clinical characteristics, including age, were analyzed in each patient. Results The number of patients per PVH grade 0, 1, 2, 3, and 4 was 26 (43.3%), 14 (23.3%), 14 (23.3%), 4 (6.7%), and 2 (3.3%), respectively. The mean age, hypertension, smoking status, AI, and CarACS were significantly different among PVH groups (Ps < 0.05). In univariate analysis, the presence of carotid arterial calcification (β = 0.483, p < 0.01), CarACS (β = 0.482, p < 0.01), and age (β = 0.360, p < 0.01) showed a significant association with PVH grade. The mean AI and lowest O2 saturation had statistically weak associations with PVH grade (β = 0.267, p < 0.01; β = -0.219, p < 0.14, respectively). In multivariate analysis, CarACS was the only factor affecting PVH grade (p < 0.04). Conclusion CarACS is associated with the severity of silent cerebrovascular lesions. Therefore, additional analysis of CarACS in OSA patients may provide more information on their cerebrovascular status. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English Korean |
| ISSN: | 1738-2637 2288-2928 |
| Relation: | https://doaj.org/toc/1738-2637; https://doaj.org/toc/2288-2928 |
| DOI: | 10.3348/jksr.2019.80.6.1214 |
| Access URL: | https://doaj.org/article/9de08dd8becb4ea89fa11c43567efe1a |
| Accession Number: | edsdoj.9de08dd8becb4ea89fa11c43567efe1a |
| Database: | Directory of Open Access Journals |
| ISSN: | 17382637 22882928 |
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| DOI: | 10.3348/jksr.2019.80.6.1214 |
| Published in: | 대한영상의학회지 |
| Language: | English Korean |