Expert opinion on the role of bilastine and bilastine-montelukast combination in the management of allergic rhinitis: An Indian perspective
| Title: | Expert opinion on the role of bilastine and bilastine-montelukast combination in the management of allergic rhinitis: An Indian perspective |
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| Authors: | Subir Jain, Sarika Verma, Santhalingam Balamurugan, K.R. Bharath Kumar Reddy, D.J. Christopher |
| Source: | The Journal of Association of Chest Physicians, Vol 11, Iss 1, Pp 1-9 (2023) |
| Publisher Information: | Wolters Kluwer Medknow Publications, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Diseases of the respiratory system |
| Subject Terms: | allergic rhinitis, antihistamine, asthma, expert opinion, guidelines, india, management, Diseases of the respiratory system, RC705-779 |
| More Details: | In India, the burden of allergic rhinitis (AR) is enormous, comprising 55% of all patients with allergies. Intranasal corticosteroids are the recommended first-line therapy for patients with moderate-to-severe AR, particularly when nasal congestion is the predominant symptom. However, second-generation antihistamines are the first line of treatment in mild AR and effectively improve symptoms, such as sneezing, itching, and rhinorrhoea. Bilastine is a second-generation H1-antihistamine indicated for the symptomatic treatment of allergic rhinoconjunctivitis in adults and adolescents over 12 years of age. Though it is an effective individual molecule for the management of AR, studies have shown that synergistic combination therapy of bilastine-montelukast has a dual action on early- and late-phase allergic reactions in AR patients with concomitant asthma. An advisory board meeting was conducted (on a virtual platform) to gain insights from Indian experts on the following: (i) burden of AR and AR with concomitant asthma in Indian settings; (ii) current unmet needs; and (iii) role and positioning of bilastine and bilastine plus montelukast combination in the management of AR and AR with concomitant asthma in adults and adolescents over 12 years of age. The experts shared their opinions based on the available scientific evidence and/or clinical expertise or experience. In this article, we have summarized the highlights of the expert panel discussion and available evidence for each of these topics. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2320-8775 2320-9089 |
| Relation: | http://www.jacpjournal.org/article.asp?issn=2320-8775;year=2023;volume=11;issue=1;spage=1;epage=9;aulast=Jain; https://doaj.org/toc/2320-8775; https://doaj.org/toc/2320-9089 |
| DOI: | 10.4103/jacp.jacp_45_22 |
| Access URL: | https://doaj.org/article/9dbc396609b54a62b2138ff00b9bd0b2 |
| Accession Number: | edsdoj.9dbc396609b54a62b2138ff00b9bd0b2 |
| Database: | Directory of Open Access Journals |
| ISSN: | 23208775 23209089 |
|---|---|
| DOI: | 10.4103/jacp.jacp_45_22 |
| Published in: | The Journal of Association of Chest Physicians |
| Language: | English |