Evolution Of Multidrug-Resistant Acinetobacter Baumannii Pneumonia In Years In Terms Of Tigecycline Treatment

Bibliographic Details
Title: Evolution Of Multidrug-Resistant Acinetobacter Baumannii Pneumonia In Years In Terms Of Tigecycline Treatment
Authors: Merve Mert Vahabi, Deniz Akyol, Deniz Dağ, Şevket Yeniyol, Olcay Buse Kenanoğlu, Oğuzhan Acet, Ayşe Uyan Önal, Uğur Önal, Seichan Ketentzi, Gamze Şanlıdağ, Gunel Quliyeva, Şükrü Dirik, Cansu Bulut Avşar, Derya Kaya, Şöhret Aydemir, Hüsnü Pullukçu, Meltem Taşbakan, Hilal Sipahi, Bilgin Arda, Oğuz Reşat Sipahi
Source: Journal of Global Antimicrobial Resistance, Vol 39, Iss , Pp 14- (2024)
Publisher Information: Elsevier, 2024.
Publication Year: 2024
Collection: LCC:Microbiology
Subject Terms: antibiotic resistance, pneumonia, tigecycline, Microbiology, QR1-502
More Details: BACKGROUND-AIM: Herein, we aimed to evaluate and compare the efficacy and susceptibility patterns of tigecycline in MDR A.baumannii pneumonia (MDRABP) in a recent vs retrospective cohort. METHODS: The outcome of adult (>18 years old) patients who were consulted by Infectious Diseases consultants due to culture proven MDRABP and treated with tigecycline between March 2016 and October 2023(Group B) was compared with a similar previously published retrospective cohort from our center(Group A, Published J Chemother. 2011 dec;23(6):345-9). Statistical analysis was performed via Chi square test and a p value less then 0.05 was considered significant. RESULTS: There were total of 202 cases of MDRABP(72 patients in group a and 130 patients in Group B). Forty-seven and 81 cases were considered as VAP in group A and B, respectively. Tigecycline and netilmicin susceptibility were significantly less in group b(Table). C/S combination and tigecycline monotherapy were significantly more common in group A while any combination therapy, colistin, fosfomycin and polymyxin b combination were more common in group B (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2213-7165
Relation: http://www.sciencedirect.com/science/article/pii/S2213716524002200; https://doaj.org/toc/2213-7165
DOI: 10.1016/j.jgar.2024.10.043
Access URL: https://doaj.org/article/9d535a4d94314bea8b3990d9fb1f0a49
Accession Number: edsdoj.9d535a4d94314bea8b3990d9fb1f0a49
Database: Directory of Open Access Journals
More Details
ISSN:22137165
DOI:10.1016/j.jgar.2024.10.043
Published in:Journal of Global Antimicrobial Resistance
Language:English