Is there any relationship between low PAPP-A levels and measures of umbilical vein and placental thickness during first trimester of pregnancy?

Bibliographic Details
Title: Is there any relationship between low PAPP-A levels and measures of umbilical vein and placental thickness during first trimester of pregnancy?
Authors: Gulsum Uysal, Sadan Tutus, Fulya Cagli, Cevdet Adiguzel
Source: İstanbul Kuzey Klinikleri, Vol 4, Iss 1, Pp 60-65 (2017)
Publisher Information: KARE Publishing, 2017.
Publication Year: 2017
Collection: LCC:Medicine
LCC:Medicine (General)
Subject Terms: first trimester, placental thickness, pregnancy-associated plasma protein a, umbilical cord, umbilical vein., Medicine, Medicine (General), R5-920
More Details: INTRODUCTION[|]Low pregnancy-associated plasma protein A (PAPP-A) level is associated with adverse perinatal outcomes. The purpose of this study was to evaluate relationship between umbilical cord diameter (UCD), umbilical vein and artery diameters (UVD, UAD), placental thickness, and PAPP-A level at gestational age of between 11 and 14 weeks.[¤]METHODS[|]UCD, UVD, UAD, and placental thickness of 246 women were assessed during ultrasound examination at between 11 and 14 weeks of gestation, as well as measurement of nuchal translucency (NT) and crown-rump length (CRL). Patients were divided into 2 groups according to PAPP-A percentile. Group 1 comprised 23 patients who had low PAPP-A (0.44 MoM, >10th percentile. Calipers used for measurement were placed inner edge to inner edge of echogenic boundaries of the vessel. Largest sections of all vessels (UV and both arteries) were evaluated. Thickest part of the placenta was used for placental thickness measurement.[¤]RESULTS[|]Narrow UCD (
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2148-4902
Relation: https://jag.journalagent.com/z4/download_fulltext.asp?pdir=nci&un=NCI-26121; https://doaj.org/toc/2148-4902
DOI: 10.14744/nci.2017.26121
Access URL: https://doaj.org/article/ade9d234c979494590afb296d34ec6b9
Accession Number: edsdoj.9d234c979494590afb296d34ec6b9
Database: Directory of Open Access Journals
More Details
ISSN:21484902
DOI:10.14744/nci.2017.26121
Published in:İstanbul Kuzey Klinikleri
Language:English