Bibliographic Details
| Title: |
Glioblastoma: Relationship between Metabolism and Immunosuppressive Microenvironment |
| Authors: |
Ainhoa Hernández, Marta Domènech, Ana M. Muñoz-Mármol, Cristina Carrato, Carmen Balana |
| Source: |
Cells, Vol 10, Iss 12, p 3529 (2021) |
| Publisher Information: |
MDPI AG, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Cytology |
| Subject Terms: |
glioblastoma, metabolism, microenvironment, Cytology, QH573-671 |
| More Details: |
Glioblastoma (GBM) is the most aggressive brain tumor in adults and is characterized by an immunosuppressive microenvironment. Different factors shaping this tumor microenvironment (TME) regulate tumor initiation, progression, and treatment response. Genetic alterations and metabolism pathways are two main elements that influence tumor immune cells and TME. In this manuscript, we review how both factors can contribute to an immunosuppressive state and overview the strategies being tested. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2073-4409 |
| Relation: |
https://www.mdpi.com/2073-4409/10/12/3529; https://doaj.org/toc/2073-4409 |
| DOI: |
10.3390/cells10123529 |
| Access URL: |
https://doaj.org/article/9ca4f10639dc4c2b845c9d24192e9992 |
| Accession Number: |
edsdoj.9ca4f10639dc4c2b845c9d24192e9992 |
| Database: |
Directory of Open Access Journals |
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