Bibliographic Details
| Title: |
Exploration of Polysaccharides from Phyllanthus emblica: Isolation, Identification, and Evaluation of Antioxidant and Anti-Glycolipid Metabolism Disorder Activities |
| Authors: |
Peng Guo, Meng Chen, Wenzhao Wang, Qiuyun Li, Xinyu Chen, Jiayue Liang, Yiyang He, Yanli Wu |
| Source: |
Molecules, Vol 29, Iss 8, p 1751 (2024) |
| Publisher Information: |
MDPI AG, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Organic chemistry |
| Subject Terms: |
polysaccharide, purification, identification, anti-glycolipid metabolism disorder activity, Organic chemistry, QD241-441 |
| More Details: |
Phyllanthus emblica is a natural medicinal herb with diverse bioactivities. Certain extracts from this herb have been confirmed to possess anti-glycolipid metabolic disorder activity. To further develop its utility value and explore its potential in combating glycolipid metabolic disorders, we designed a series of experiments to investigate the structure, antioxidant activity, and anti-glycolipid metabolic disorder activity of Phyllanthus emblica polysaccharides. In this study, we extracted and purified polysaccharides from Phyllanthus emblica and thoroughly analyzed their structure using various techniques, including NMR, methylation analysis, and surface-enhanced Raman spectroscopy. We investigated the hypolipidemic and anti-glycolipid metabolism disorder activity of Phyllanthus emblica polysaccharides for the first time utilizing oleic acid (OA) and advanced glycation end products (AGEs) as inducers. Additionally, the antioxidant activity of Phyllanthus emblica polysaccharides was assessed in vitro. These findings lay the groundwork for future investigations into the potential application of Phyllanthus emblica polysaccharides as an intervention for preventing and treating diabetes. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1420-3049 |
| Relation: |
https://www.mdpi.com/1420-3049/29/8/1751; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules29081751 |
| Access URL: |
https://doaj.org/article/9c9a395459584d39bbb20f11c98770d8 |
| Accession Number: |
edsdoj.9c9a395459584d39bbb20f11c98770d8 |
| Database: |
Directory of Open Access Journals |
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