Bibliographic Details
| Title: |
SALM4 negatively regulates NMDA receptor function and fear memory consolidation |
| Authors: |
Eunkyung Lie, Yeji Yeo, Eun-Jae Lee, Wangyong Shin, Kyungdeok Kim, Kyung Ah Han, Esther Yang, Tae-Yong Choi, Mihyun Bae, Suho Lee, Seung Min Um, Se-Young Choi, Hyun Kim, Jaewon Ko, Eunjoon Kim |
| Source: |
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
Biology (General), QH301-705.5 |
| More Details: |
To elucidate the role of synaptic cell adhesion-like molecule 4 (SALM4) in altering synaptic function in the context of fear memory, Lie at al performed behavioural and electrophysiological assessments of SALM4 knockout mice undergoing cued fear, spatial, and object-recognition memory tasks. They demonstrated that SALM4 suppresses heightened GluN2B-expressing NMDA receptor function specifically during fear memory consolidation. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-021-02656-3 |
| Access URL: |
https://doaj.org/article/9c6821f43b5b415bb8a595e34ac8759f |
| Accession Number: |
edsdoj.9c6821f43b5b415bb8a595e34ac8759f |
| Database: |
Directory of Open Access Journals |
