Evaluating a screener to quantify PTSD risk using emergency care information: a proof of concept study

Bibliographic Details
Title: Evaluating a screener to quantify PTSD risk using emergency care information: a proof of concept study
Authors: Willem F. van der Mei, Anna C. Barbano, Andrew Ratanatharathorn, Richard A. Bryant, Douglas L. Delahanty, Terri A. deRoon-Cassini, Betty S. Lai, Sarah R. Lowe, Yutaka J. Matsuoka, Miranda Olff, Wei Qi, Ulrich Schnyder, Soraya Seedat, Ronald C. Kessler, Karestan C. Koenen, Arieh Y. Shalev, International Consortium to Predict PTSD
Source: BMC Emergency Medicine, Vol 20, Iss 1, Pp 1-11 (2020)
Publisher Information: BMC, 2020.
Publication Year: 2020
Collection: LCC:Special situations and conditions
LCC:Medical emergencies. Critical care. Intensive care. First aid
Subject Terms: Emergency care admissions, Post-traumatic stress disorder, Peritraumatic symptoms, Sequential prediction, Mega-analysis, Special situations and conditions, RC952-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
More Details: Abstract Background Previous work has indicated that post-traumatic stress disorder (PTSD) symptoms, measured by the Clinician-Administered PTSD Scale (CAPS) within 60 days of trauma exposure, can reliably produce likelihood estimates of chronic PTSD among trauma survivors admitted to acute care centers. Administering the CAPS is burdensome, requires skilled professionals, and relies on symptoms that are not fully expressed upon acute care admission. Predicting chronic PTSD from peritraumatic responses, which are obtainable upon acute care admission, has yielded conflicting results, hence the rationale for a stepwise screening-and-prediction practice. This work explores the ability of peritraumatic responses to produce risk likelihood estimates of early CAPS-based PTSD symptoms indicative of chronic PTSD risk. It specifically evaluates the Peritraumatic Dissociative Experiences Questionnaire (PDEQ) as a risk-likelihood estimator. Methods We used individual participant data (IPD) from five acute care studies that used both the PDEQ and the CAPS (n = 647). Logistic regression calculated the probability of having CAPS scores ≥ 40 between 30 and 60 days after trauma exposure across the range of initial PDEQ scores, and evaluated the added contribution of age, sex, trauma type, and prior trauma exposure. Brier scores, area under the receiver-operating characteristic curve (AUC), and the mean slope of the calibration line evaluated the accuracy and precision of the predicted probabilities. Results Twenty percent of the sample had CAPS ≥ 40. PDEQ severity significantly predicted having CAPS ≥ 40 symptoms (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-227X
Relation: http://link.springer.com/article/10.1186/s12873-020-00308-z; https://doaj.org/toc/1471-227X
DOI: 10.1186/s12873-020-00308-z
Access URL: https://doaj.org/article/9c44ebaa28de45d195e02855625b95a6
Accession Number: edsdoj.9c44ebaa28de45d195e02855625b95a6
Database: Directory of Open Access Journals
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More Details
ISSN:1471227X
DOI:10.1186/s12873-020-00308-z
Published in:BMC Emergency Medicine
Language:English