Bibliographic Details
| Title: |
GWAS of epigenetic aging rates in blood reveals a critical role for TERT |
| Authors: |
Ake T. Lu, Luting Xue, Elias L. Salfati, Brian H. Chen, Luigi Ferrucci, Daniel Levy, Roby Joehanes, Joanne M. Murabito, Douglas P. Kiel, Pei-Chien Tsai, Idil Yet, Jordana T. Bell, Massimo Mangino, Toshiko Tanaka, Allan F. McRae, Riccardo E. Marioni, Peter M. Visscher, Naomi R. Wray, Ian J. Deary, Morgan E. Levine, Austin Quach, Themistocles Assimes, Philip S. Tsao, Devin Absher, James D. Stewart, Yun Li, Alex P. Reiner, Lifang Hou, Andrea A. Baccarelli, Eric A. Whitsel, Abraham Aviv, Alexia Cardona, Felix R. Day, Nicholas J. Wareham, John R. B. Perry, Ken K. Ong, Kenneth Raj, Kathryn L. Lunetta, Steve Horvath |
| Source: |
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
| Publisher Information: |
Nature Portfolio, 2018. |
| Publication Year: |
2018 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Epigenetic clocks based on DNA methylation levels are estimators of chronological age. Here, the authors perform a GWAS of epigenetic aging rates in blood and find SNP variants in the TERT locus associated with increased intrinsic epigenetic age are also associated with longer telomeres. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-017-02697-5 |
| Access URL: |
https://doaj.org/article/9c04cc5045d14339bb52c91c1cd6b779 |
| Accession Number: |
edsdoj.9c04cc5045d14339bb52c91c1cd6b779 |
| Database: |
Directory of Open Access Journals |
