Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program

Bibliographic Details
Title: Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program
Authors: Emanuel Wyler, Vedran Franke, Jennifer Menegatti, Christine Kocks, Anastasiya Boltengagen, Samantha Praktiknjo, Barbara Walch-Rückheim, Jens Bosse, Nikolaus Rajewsky, Friedrich Grässer, Altuna Akalin, Markus Landthaler
Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Publisher Information: Nature Portfolio, 2019.
Publication Year: 2019
Collection: LCC:Science
Subject Terms: Science
More Details: Herpes simplex virus 1 (HSV-1) induces major reprogramming of the host cell environment. Here, the authors profile the transcriptomes of individual HSV-1-infected human fibroblasts and provide evidence of an antiviral program mediated by the activation of the host transcription factor NRF2.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-019-12894-z
Access URL: https://doaj.org/article/9b9106fe09bb41628a077aaba85373ab
Accession Number: edsdoj.9b9106fe09bb41628a077aaba85373ab
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-019-12894-z
Published in:Nature Communications
Language:English