Title: |
Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program |
Authors: |
Emanuel Wyler, Vedran Franke, Jennifer Menegatti, Christine Kocks, Anastasiya Boltengagen, Samantha Praktiknjo, Barbara Walch-Rückheim, Jens Bosse, Nikolaus Rajewsky, Friedrich Grässer, Altuna Akalin, Markus Landthaler |
Source: |
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
Publisher Information: |
Nature Portfolio, 2019. |
Publication Year: |
2019 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Herpes simplex virus 1 (HSV-1) induces major reprogramming of the host cell environment. Here, the authors profile the transcriptomes of individual HSV-1-infected human fibroblasts and provide evidence of an antiviral program mediated by the activation of the host transcription factor NRF2. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-019-12894-z |
Access URL: |
https://doaj.org/article/9b9106fe09bb41628a077aaba85373ab |
Accession Number: |
edsdoj.9b9106fe09bb41628a077aaba85373ab |
Database: |
Directory of Open Access Journals |